Ionotropically gelled novel hydrogel beads: Preparation, characterization and in vitro evaluation
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چکیده
منابع مشابه
Ionotropically Gelled Novel Hydrogel Beads: Preparation, Characterization and In vitro Evaluation
Prolonged release drug delivery system of stavudine was made by ionotropic gelation and polyelectrolyte complexation technique. Cross-linking reinforced chitosan-gellan complex beads were prepared by gelation of anionic gellan gum, the primary polymer, with oppositely charged counter ion to form beads which were further complexed with chitosan as a polyelectrolyte. The effect of this polymer on...
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The work investigates the development and optimization of ionotropically-gelled mucoadhesive beads composed of tamarind seed polysaccharide (TSP)-alginate polymer-blend for oral delivery of metformin HCl using 32 factorial design. The optimized mucoadhesive beads exhibited 94.86 ± 3.92 % drug encapsulation efficiency and good mucoadhesivity with the biological membrane in wash-off test, and sus...
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BACKGROUND: The development of injectable sustained-release products are of great interest to veterinary pharmaceuticals and animal health business. Recently, great attention has been paid to in situ gel-forming chitosan/beta-glycerophosphate (chitosan/β-GP) solutions due to their good biodegradability and thermosensitivity. OBJECTIVES: The general aim of this study was to prepare a novel in si...
متن کاملpreparation and in vitro evaluation of a novel chitosan-based hydrogel for injectable delivery of enrofloxacin
background: the development of injectable sustained-release products are of great interest to veterinary pharmaceuticals and animal health business. recently, great attention has been paid to in situ gel-forming chitosan/beta-glycerophosphate (chitosan/β-gp) solutions due to their good biodegradability and thermosensitivity. objectives: the general aim of this study was to prepare a novel in si...
متن کاملA Novel Domperidone Hydrogel: Preparation, Characterization, Pharmacokinetic, and Pharmacodynamic Properties
The purpose of the present study was to prepare a novel domperidone hydrogel. The domperidone dispersion was prepared by the solvent evaporation method. The characteristics of domperidone dispersion were measured by dynamic light scattering (DLS), scanning electronic microscopy (SEM), differential scanning calorimetry (DSC), X-ray diffractometry, and solubility test, respectively. Domperidone h...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmaceutical Sciences
سال: 2011
ISSN: 0250-474X
DOI: 10.4103/0250-474x.98988